A80T (p.Ala80Thr) variant of CD4 (T-cell surface glycoprotein CD4)
A80T (p.Ala80Thr) in CD4 (T-cell surface glycoprotein CD4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data and structural context.
A80T (p.Ala80Thr) variant details
- p.Ala80Thr
- cosmic curated COSV50589
- 1000Genomes rs201343243
- ExAC rs201343243
- TOPMed rs201343243
- Missense
- Variant Prioritization Score for Impact Estimate 0.0945
- REVEL 0.07
- MetaLR 0.10
- MetaSVM -1.07
- CADD 0.05
- PolyPhen-2 0.00
- SIFT 0.11
- Most common in the African/African-American population (allele frequency 0.00031)
- Structural context available