A80S (p.Ala80Ser) variant of CD4 (T-cell surface glycoprotein CD4)
A80S (p.Ala80Ser) in CD4 (T-cell surface glycoprotein CD4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data and structural context.
A80S (p.Ala80Ser) variant details
- p.Ala80Ser
- 1000Genomes rs201343243
- ExAC rs201343243
- TOPMed rs201343243
- gnomAD rs201343243
- Missense
- Variant Prioritization Score for Impact Estimate 0.1
- REVEL 0.09
- MetaLR 0.10
- MetaSVM -1.04
- CADD 0.03
- PolyPhen-2 0.06
- SIFT 0.12
- Most common in the African/African-American population (allele frequency 0.00041)
- Structural context available