A43P (p.Ala43Pro) variant of CD4 (T-cell surface glycoprotein CD4)
A43P (p.Ala43Pro) in CD4 (T-cell surface glycoprotein CD4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
A43P (p.Ala43Pro) variant details
- p.Ala43Pro
- TOPMed rs1401043905
- gnomAD rs1401043905
- Missense
- Variant Prioritization Score for Impact Estimate 0.195
- REVEL 0.24
- MetaLR 0.22
- MetaSVM -0.93
- CADD 2.54
- PolyPhen-2 0.20
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 8.8e-05)
- Structural context available