A21G (p.Ala21Gly) variant of CD4 (T-cell surface glycoprotein CD4)
A21G (p.Ala21Gly) in CD4 (T-cell surface glycoprotein CD4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
A21G (p.Ala21Gly) variant details
- p.Ala21Gly
- TOPMed rs893226381
- Missense
- Variant Prioritization Score for Impact Estimate 0.115
- REVEL 0.06
- MetaLR 0.10
- MetaSVM -1.02
- CADD 9.18
- PolyPhen-2 0.82
- SIFT 0.18
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available