V42M (p.Val42Met) variant of CD276 (CD276 antigen)
V42M (p.Val42Met) in CD276 (CD276 antigen) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data, published literature, and structural context.
V42M (p.Val42Met) variant details
- p.Val42Met
- gnomAD 15-73702299-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.347
- REVEL 0.18
- CADD 22.90
- PolyPhen-2 0.80
- SIFT 0.19
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available