V42L (p.Val42Leu) variant of CD276 (CD276 antigen)
V42L (p.Val42Leu) in CD276 (CD276 antigen) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
V42L (p.Val42Leu) variant details
- p.Val42Leu
- TOPMed rs1243448980
- gnomAD rs1243448980
- Missense
- Variant Prioritization Score for Impact Estimate 0.258
- REVEL 0.07
- CADD 16.60
- PolyPhen-2 0.03
- SIFT 0.64
- Most common in the East Asian population (allele frequency 0.0001)
- Structural context available