V38L (p.Val38Leu) variant of CD276 (CD276 antigen)
V38L (p.Val38Leu) in CD276 (CD276 antigen) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
V38L (p.Val38Leu) variant details
- p.Val38Leu
- ExAC rs774478067
- TOPMed rs774478067
- gnomAD rs774478067
- Missense
- Variant Prioritization Score for Impact Estimate 0.395
- REVEL 0.15
- CADD 23.50
- PolyPhen-2 0.51
- SIFT 0.10
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available