V12M (p.Val12Met) variant of CD276 (CD276 antigen)
V12M (p.Val12Met) in CD276 (CD276 antigen) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data and structural context.
V12M (p.Val12Met) variant details
- p.Val12Met
- ExAC rs768034811
- gnomAD rs768034811
- Missense
- Variant Prioritization Score for Impact Estimate 0.114
- REVEL 0.03
- CADD 15.30
- PolyPhen-2 0.01
- SIFT 0.07
- Most common in the South Asian population (allele frequency 2.3e-05)
- Structural context available