V12L (p.Val12Leu) variant of CD276 (CD276 antigen)
V12L (p.Val12Leu) in CD276 (CD276 antigen) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data and structural context.
V12L (p.Val12Leu) variant details
- p.Val12Leu
- ExAC rs768034811
- gnomAD rs768034811
- Missense
- Variant Prioritization Score for Impact Estimate 0.0971
- REVEL 0.02
- CADD 12.20
- PolyPhen-2 0.01
- SIFT 0.10
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available