S53F (p.Ser53Phe) variant of CD276 (CD276 antigen)
S53F (p.Ser53Phe) in CD276 (CD276 antigen) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data, published literature, and structural context.
S53F (p.Ser53Phe) variant details
- p.Ser53Phe
- gnomAD 15-73702333-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.271
- REVEL 0.13
- CADD 17.80
- PolyPhen-2 0.12
- SIFT 0.01
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available