R4L (p.Arg4Leu) variant of CD276 (CD276 antigen)
R4L (p.Arg4Leu) in CD276 (CD276 antigen) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.06 / 1. The record also includes population frequency data and structural context.
R4L (p.Arg4Leu) variant details
- p.Arg4Leu
- TOPMed rs1232227175
- gnomAD rs1232227175
- Missense
- Variant Prioritization Score for Impact Estimate 0.0565
- REVEL 0.01
- CADD 5.32
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available