L21P (p.Leu21Pro) variant of CD276 (CD276 antigen)
L21P (p.Leu21Pro) in CD276 (CD276 antigen) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data, published literature, and structural context.
L21P (p.Leu21Pro) variant details
- p.Leu21Pro
- gnomAD 15-73699701-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.422
- REVEL 0.27
- CADD 25.00
- PolyPhen-2 0.99
- SIFT 0.08
- Population evidence available
- Structural context available
- Literature evidence available