G43D (p.Gly43Asp) variant of CD276 (CD276 antigen)
G43D (p.Gly43Asp) in CD276 (CD276 antigen) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data, published literature, and structural context.
G43D (p.Gly43Asp) variant details
- p.Gly43Asp
- gnomAD 15-73702303-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.416
- REVEL 0.44
- CADD 20.10
- PolyPhen-2 0.04
- SIFT 0.12
- Most common in the Non-Finnish European population (allele frequency 8.1e-06)
- Structural context available
- Literature evidence available