G27V (p.Gly27Val) variant of CD276 (CD276 antigen)
G27V (p.Gly27Val) in CD276 (CD276 antigen) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data, published literature, and structural context.
G27V (p.Gly27Val) variant details
- p.Gly27Val
- gnomAD 15-73702255-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.448
- REVEL 0.23
- CADD 33.00
- PolyPhen-2 1.00
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 3.6e-06)
- Structural context available
- Literature evidence available