E35K (p.Glu35Lys) variant of CD276 (CD276 antigen)
E35K (p.Glu35Lys) in CD276 (CD276 antigen) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
E35K (p.Glu35Lys) variant details
- p.Glu35Lys
- ExAC rs768902183
- TOPMed rs768902183
- Missense
- Variant Prioritization Score for Impact Estimate 0.379
- REVEL 0.20
- CADD 24.00
- PolyPhen-2 0.05
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available