D45G (p.Asp45Gly) variant of CD276 (CD276 antigen)
D45G (p.Asp45Gly) in CD276 (CD276 antigen) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data and structural context.
D45G (p.Asp45Gly) variant details
- p.Asp45Gly
- TOPMed rs1900426724
- Missense
- Variant Prioritization Score for Impact Estimate 0.521
- REVEL 0.45
- CADD 24.50
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available