C50Y (p.Cys50Tyr) variant of CD276 (CD276 antigen)
C50Y (p.Cys50Tyr) in CD276 (CD276 antigen) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.63 / 1. The record also includes population frequency data, published literature, and structural context.
C50Y (p.Cys50Tyr) variant details
- p.Cys50Tyr
- gnomAD 15-73702324-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.628
- REVEL 0.53
- CADD 25.90
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available