C50G (p.Cys50Gly) variant of CD276 (CD276 antigen)
C50G (p.Cys50Gly) in CD276 (CD276 antigen) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data, published literature, and structural context.
C50G (p.Cys50Gly) variant details
- p.Cys50Gly
- gnomAD 15-73702323-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.505
- REVEL 0.42
- CADD 25.50
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available