V61L (p.Val61Leu) variant of CARD9 (Q9H257)
V61L (p.Val61Leu) in CARD9 (Q9H257) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data and structural context.
V61L (p.Val61Leu) variant details
- p.Val61Leu
- ExAC rs765010252
- gnomAD rs765010252
- Missense
- Variant Prioritization Score for Impact Estimate 0.426
- REVEL 0.19
- CADD 22.80
- PolyPhen-2 0.79
- SIFT 0.05
- Most common in the Latino/Admixed American population (allele frequency 2.3e-05)
- Structural context available