T121S (p.Thr121Ser) variant of CARD9 (Q9H257)
T121S (p.Thr121Ser) in CARD9 (Q9H257) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data.
T121S (p.Thr121Ser) variant details
- p.Thr121Ser
- gnomAD rs1434258703
- Missense
- Variant Prioritization Score for Impact Estimate 0.283
- REVEL 0.03
- CADD 8.45
- PolyPhen-2 0.00
- SIFT 0.59
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)