L65P (p.Leu65Pro) variant of CARD9 (Q9H257)
L65P (p.Leu65Pro) in CARD9 (Q9H257) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.64 / 1. The record also includes population frequency data and structural context.
L65P (p.Leu65Pro) variant details
- p.Leu65Pro
- gnomAD rs1276381998
- Missense
- Variant Prioritization Score for Impact Estimate 0.639
- REVEL 0.64
- CADD 25.80
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the REMAINING population (allele frequency 1.8e-05)
- Structural context available