K74R (p.Lys74Arg) variant of CARD9 (Q9H257)
K74R (p.Lys74Arg) in CARD9 (Q9H257) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data.
K74R (p.Lys74Arg) variant details
- p.Lys74Arg
- gnomAD rs1177629322
- Missense
- Variant Prioritization Score for Impact Estimate 0.326
- REVEL 0.08
- CADD 16.90
- PolyPhen-2 0.14
- SIFT 1.00
- Most common in the South Asian population (allele frequency 3.6e-05)