H73R (p.His73Arg) variant of CARD9 (Q9H257)
H73R (p.His73Arg) in CARD9 (Q9H257) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data.
H73R (p.His73Arg) variant details
- p.His73Arg
- TOPMed rs1383238223
- gnomAD rs1383238223
- Missense
- Variant Prioritization Score for Impact Estimate 0.165
- REVEL 0.06
- CADD 16.80
- PolyPhen-2 0.03
- SIFT 0.34
- Most common in the African/African-American population (allele frequency 2.4e-05)