S22T (p.Ser22Thr) variant of CALCB (P10092)
S22T (p.Ser22Thr) in CALCB (P10092) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data, published literature, and structural context.
S22T (p.Ser22Thr) variant details
- p.Ser22Thr
- gnomAD 11-15074783-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.226
- REVEL 0.09
- CADD 21.60
- PolyPhen-2 0.06
- SIFT 0.46
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available