S22R (p.Ser22Arg) variant of CALCB (P10092)
S22R (p.Ser22Arg) in CALCB (P10092) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
S22R (p.Ser22Arg) variant details
- p.Ser22Arg
- gnomAD rs1167372632
- Missense
- Variant Prioritization Score for Impact Estimate 0.167
- REVEL 0.08
- CADD 21.00
- PolyPhen-2 0.01
- SIFT 0.36
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available