P8S (p.Pro8Ser) variant of CALCB (P10092)
P8S (p.Pro8Ser) in CALCB (P10092) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
P8S (p.Pro8Ser) variant details
- p.Pro8Ser
- TOPMed rs1336814260
- gnomAD rs1336814260
- Missense
- Variant Prioritization Score for Impact Estimate 0.232
- REVEL 0.04
- CADD 16.30
- PolyPhen-2 0.02
- SIFT 0.13
- Most common in the Latino/Admixed American population (allele frequency 0.00039)
- Structural context available