L17P (p.Leu17Pro) variant of CALCB (P10092)
L17P (p.Leu17Pro) in CALCB (P10092) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data and structural context.
L17P (p.Leu17Pro) variant details
- p.Leu17Pro
- ExAC rs752957836
- gnomAD rs752957836
- Missense
- Variant Prioritization Score for Impact Estimate 0.427
- REVEL 0.41
- CADD 32.00
- PolyPhen-2 0.95
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available