F9S (p.Phe9Ser) variant of CALCB (P10092)
F9S (p.Phe9Ser) in CALCB (P10092) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; high impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
F9S (p.Phe9Ser) variant details
- p.Phe9Ser
- NCI-TCGA TCGA novel
- Variant assessed as somatic; high impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.283
- REVEL 0.21
- CADD 25.40
- PolyPhen-2 0.11
- SIFT 0.01
- UniProt: Variant assessed as somatic; high impact.
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available