F6L (p.Phe6Leu) variant of CALCB (P10092)
F6L (p.Phe6Leu) in CALCB (P10092) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
F6L (p.Phe6Leu) variant details
- p.Phe6Leu
- ExAC rs773655356
- TOPMed rs773655356
- gnomAD rs773655356
- Missense
- Variant Prioritization Score for Impact Estimate 0.136
- REVEL 0.03
- CADD 21.30
- PolyPhen-2 0.01
- SIFT 0.21
- Most common in the Non-Finnish European population (allele frequency 3.6e-06)
- Structural context available