S64T (p.Ser64Thr) variant of CALCA (P06881)
S64T (p.Ser64Thr) in CALCA (P06881) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.06 / 1. The record also includes population frequency data, published literature, and structural context.
S64T (p.Ser64Thr) variant details
- p.Ser64Thr
- gnomAD 11-14969971-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.0635
- REVEL 0.03
- CADD 5.66
- PolyPhen-2 0.17
- SIFT 0.34
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available