M61T (p.Met61Thr) variant of CALCA (P06881)
M61T (p.Met61Thr) in CALCA (P06881) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data, published literature, and structural context.
M61T (p.Met61Thr) variant details
- p.Met61Thr
- gnomAD 11-14968950-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.335
- REVEL 0.30
- CADD 23.50
- PolyPhen-2 0.09
- SIFT 0.00
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available