L32P (p.Leu32Pro) variant of CALCA (P06881)
L32P (p.Leu32Pro) in CALCA (P06881) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data.
L32P (p.Leu32Pro) variant details
- p.Leu32Pro
- ExAC rs782307920
- TOPMed rs782307920
- gnomAD rs782307920
- Missense
- Variant Prioritization Score for Impact Estimate 0.242
- REVEL 0.22
- CADD 22.20
- PolyPhen-2 0.95
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 2.9e-05)