G2S (p.Gly2Ser) variant of CALCA (P06881)
G2S (p.Gly2Ser) in CALCA (P06881) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
G2S (p.Gly2Ser) variant details
- p.Gly2Ser
- 1000Genomes rs34587547
- ESP rs34587547
- ExAC rs34587547
- TOPMed rs34587547
- Missense
- Variant Prioritization Score for Impact Estimate 0.258
- REVEL 0.13
- CADD 18.80
- PolyPhen-2 0.18
- SIFT 0.16
- Most common in the 1KG:GWD population (allele frequency 0.013)
- Structural context available