G2D (p.Gly2Asp) variant of CALCA (P06881)
G2D (p.Gly2Asp) in CALCA (P06881) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data, published literature, and structural context.
G2D (p.Gly2Asp) variant details
- p.Gly2Asp
- gnomAD 11-14971188-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.303
- REVEL 0.13
- CADD 24.30
- PolyPhen-2 0.86
- SIFT 0.04
- Most common in the Non-Finnish European population (allele frequency 3.6e-06)
- Structural context available
- Literature evidence available