F6L (p.Phe6Leu) variant of CALCA (P06881)
F6L (p.Phe6Leu) in CALCA (P06881) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data.
F6L (p.Phe6Leu) variant details
- p.Phe6Leu
- ESP rs375202775
- ExAC rs375202775
- TOPMed rs375202775
- gnomAD rs375202775
- Missense
- Variant Prioritization Score for Impact Estimate 0.25
- REVEL 0.06
- CADD 19.30
- PolyPhen-2 0.01
- SIFT 0.47
- Most common in the African/African-American population (allele frequency 0.00058)