A63D (p.Ala63Asp) variant of CALCA (P06881)
A63D (p.Ala63Asp) in CALCA (P06881) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data.
A63D (p.Ala63Asp) variant details
- p.Ala63Asp
- cosmic curated COSV59027
- ExAC rs782654358
- TOPMed rs782654358
- gnomAD rs782654358
- Missense
- Variant Prioritization Score for Impact Estimate 0.328
- REVEL 0.07
- CADD 20.60
- PolyPhen-2 0.84
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 0.0017)