G22W (p.Gly22Trp) variant of CACNA1A (O00555)
G22W (p.Gly22Trp) in CACNA1A (O00555) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.66 / 1. The record also includes population frequency data and structural context.
G22W (p.Gly22Trp) variant details
- p.Gly22Trp
- cosmic curated COSV64193
- Missense
- Variant Prioritization Score for Impact Estimate 0.661
- REVEL 0.55
- MetaLR 0.84
- MetaSVM 0.79
- CADD 27.80
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available