Y59H (p.Tyr59His) variant of C5 (Complement C5)
Y59H (p.Tyr59His) in C5 (Complement C5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
Y59H (p.Tyr59His) variant details
- p.Tyr59His
- gnomAD rs1485607759
- Missense
- Variant Prioritization Score for Impact Estimate 0.354
- REVEL 0.19
- MetaLR 0.13
- MetaSVM -0.85
- CADD 26.20
- PolyPhen-2 0.82
- SIFT 0.00
- Population evidence available
- Structural context available