V160A (p.Val160Ala) variant of C5 (Complement C5)
V160A (p.Val160Ala) in C5 (Complement C5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
V160A (p.Val160Ala) variant details
- p.Val160Ala
- ExAC rs756209447
- TOPMed rs756209447
- gnomAD rs756209447
- Missense
- Variant Prioritization Score for Impact Estimate 0.342
- REVEL 0.26
- MetaLR 0.33
- MetaSVM -0.67
- CADD 23.60
- PolyPhen-2 0.28
- SIFT 0.11
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available