T159N (p.Thr159Asn) variant of C5 (Complement C5)
T159N (p.Thr159Asn) in C5 (Complement C5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
T159N (p.Thr159Asn) variant details
- p.Thr159Asn
- ExAC rs778024861
- gnomAD rs778024861
- Missense
- Variant Prioritization Score for Impact Estimate 0.383
- REVEL 0.38
- MetaLR 0.46
- MetaSVM -0.50
- CADD 23.90
- PolyPhen-2 0.88
- SIFT 0.03
- Population evidence available
- Structural context available