Q19R (p.Gln19Arg) variant of C5 (Complement C5)
Q19R (p.Gln19Arg) in C5 (Complement C5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
Q19R (p.Gln19Arg) variant details
- p.Gln19Arg
- gnomAD rs2047661225
- Missense
- Variant Prioritization Score for Impact Estimate 0.412
- REVEL 0.33
- MetaLR 0.23
- MetaSVM -0.59
- CADD 26.50
- PolyPhen-2 0.92
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available