K156E (p.Lys156Glu) variant of C5 (Complement C5)
K156E (p.Lys156Glu) in C5 (Complement C5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
K156E (p.Lys156Glu) variant details
- p.Lys156Glu
- gnomAD rs1333422218
- Missense
- Variant Prioritization Score for Impact Estimate 0.251
- REVEL 0.14
- MetaLR 0.23
- MetaSVM -0.90
- CADD 21.30
- PolyPhen-2 0.13
- SIFT 0.02
- Most common in the Latino/Admixed American population (allele frequency 2.3e-05)
- Structural context available