G95R (p.Gly95Arg) variant of C5 (Complement C5)
G95R (p.Gly95Arg) in C5 (Complement C5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
G95R (p.Gly95Arg) variant details
- p.Gly95Arg
- gnomAD rs1435145383
- Missense
- Variant Prioritization Score for Impact Estimate 0.206
- REVEL 0.01
- MetaLR 0.05
- MetaSVM -1.04
- CADD 5.11
- PolyPhen-2 0.00
- SIFT 0.55
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available