D151G (p.Asp151Gly) variant of C5 (Complement C5)
D151G (p.Asp151Gly) in C5 (Complement C5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
D151G (p.Asp151Gly) variant details
- p.Asp151Gly
- gnomAD rs1190615111
- Missense
- Variant Prioritization Score for Impact Estimate 0.453
- REVEL 0.35
- MetaLR 0.38
- MetaSVM -0.27
- CADD 26.50
- PolyPhen-2 0.50
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.9e-06)
- Structural context available