R157W (p.Arg157Trp) variant of BRD3 (Bromodomain-containing protein 3)
R157W (p.Arg157Trp) in BRD3 (Bromodomain-containing protein 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.54 / 1. The record also includes population frequency data.
R157W (p.Arg157Trp) variant details
- p.Arg157Trp
- ExAC rs768238584
- gnomAD rs768238584
- Missense
- Variant Prioritization Score for Impact Estimate 0.537
- REVEL 0.35
- CADD 29.10
- PolyPhen-2 0.90
- SIFT 0.00
- Most common in the REMAINING population (allele frequency 3.4e-05)