R157Q (p.Arg157Gln) variant of BRD3 (Bromodomain-containing protein 3)
R157Q (p.Arg157Gln) in BRD3 (Bromodomain-containing protein 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data.
R157Q (p.Arg157Gln) variant details
- p.Arg157Gln
- ExAC rs748991694
- TOPMed rs748991694
- gnomAD rs748991694
- Missense
- Variant Prioritization Score for Impact Estimate 0.377
- REVEL 0.12
- CADD 23.00
- PolyPhen-2 0.30
- SIFT 0.05
- Most common in the African/African-American population (allele frequency 3.4e-05)