P24L (p.Pro24Leu) variant of BRD3 (Bromodomain-containing protein 3)
P24L (p.Pro24Leu) in BRD3 (Bromodomain-containing protein 3) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; high impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data.
P24L (p.Pro24Leu) variant details
- p.Pro24Leu
- ExAC rs200923400
- TOPMed rs200923400
- gnomAD rs200923400
- NCI-TCGA TCGA novel
- Variant assessed as somatic; high impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.515
- REVEL 0.33
- CADD 26.10
- PolyPhen-2 1.00
- SIFT 0.00
- UniProt: Variant assessed as somatic; high impact.
- Most common in the Finnish in Finland (FIN) population (allele frequency 9.4e-05)