P118L (p.Pro118Leu) variant of BRD3 (Bromodomain-containing protein 3)
P118L (p.Pro118Leu) in BRD3 (Bromodomain-containing protein 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.54 / 1. The record also includes population frequency data.
P118L (p.Pro118Leu) variant details
- p.Pro118Leu
- cosmic curated COSV57701
- 1000Genomes rs565005949
- TOPMed rs565005949
- Missense
- Variant Prioritization Score for Impact Estimate 0.54
- REVEL 0.36
- CADD 27.70
- PolyPhen-2 0.59
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 3.2e-05)