M108I (p.Met108Ile) variant of BRD3 (Bromodomain-containing protein 3)
M108I (p.Met108Ile) in BRD3 (Bromodomain-containing protein 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data.
M108I (p.Met108Ile) variant details
- p.Met108Ile
- gnomAD rs1412525735
- Missense
- Variant Prioritization Score for Impact Estimate 0.52
- REVEL 0.33
- CADD 25.20
- PolyPhen-2 0.94
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)