I12T (p.Ile12Thr) variant of BRD3 (Bromodomain-containing protein 3)
I12T (p.Ile12Thr) in BRD3 (Bromodomain-containing protein 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data.
I12T (p.Ile12Thr) variant details
- p.Ile12Thr
- ExAC rs771882425
- gnomAD rs771882425
- Missense
- Variant Prioritization Score for Impact Estimate 0.296
- REVEL 0.17
- CADD 20.60
- PolyPhen-2 0.00
- SIFT 0.08
- Most common in the South Asian population (allele frequency 1.2e-05)